Ion channel gene GJB2 influences the intercellular communication by Up-regulating the SPP1 signaling pathway identified by the single-cell RNA sequencing in lung adenocarcinoma

OBJECTIVE: Firstly, observe the prognostic significance and the biological functional effects of gap junction protein beta 2 (GJB2 or Cx26) in lung adenocarcinoma (LUAD). Subsequently, explore the role played by GJB2 in intercellular communication by single-cell RNA sequencing. METHOD: We made a dif...

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Detalles Bibliográficos
Autores principales: Liu, Zuo, Xiao, Zengtuan, Wang, Xiaofei, Zhang, Lianmin, Zhang, Zhenfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175797/
https://www.ncbi.nlm.nih.gov/pubmed/37188183
http://dx.doi.org/10.3389/fonc.2023.1146976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175797/
https://www.ncbi.nlm.nih.gov/pubmed/37188183
http://dx.doi.org/10.3389/fonc.2023.1146976

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