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Switch-like compaction of poly(ADP-ribose) upon cation binding

Poly(ADP-ribose) (PAR) is a homopolymer of adenosine diphosphate ribose that is added to proteins as a posttranslational modification to regulate numerous cellular processes. PAR also serves as a scaffold for protein binding in macromolecular complexes, including biomolecular condensates. It remains...

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Detalles Bibliográficos
Autores principales: Badiee, Mohsen, Kenet, Adam L., Ganser, Laura R., Paul, Tapas, Myong, Sua, Leung, Anthony K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175808/
https://www.ncbi.nlm.nih.gov/pubmed/37126687
http://dx.doi.org/10.1073/pnas.2215068120