The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense desmoplastic stroma that impedes drug delivery, reduces parenchymal blood flow, and suppresses the anti-tumor immune response. The extracellular matrix and abundance of stromal cells result in severe hypoxia within the tumor microen...

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Detalles Bibliográficos
Autores principales: Strickland, Lincoln N., Faraoni, Erika Y., Ruan, Wei, Yuan, Xiaoyi, Eltzschig, Holger K., Bailey-Lundberg, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175829/
https://www.ncbi.nlm.nih.gov/pubmed/37187740
http://dx.doi.org/10.3389/fimmu.2023.1163585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175829/
https://www.ncbi.nlm.nih.gov/pubmed/37187740
http://dx.doi.org/10.3389/fimmu.2023.1163585

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