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The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense desmoplastic stroma that impedes drug delivery, reduces parenchymal blood flow, and suppresses the anti-tumor immune response. The extracellular matrix and abundance of stromal cells result in severe hypoxia within the tumor microen...

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Detalles Bibliográficos
Autores principales:	Strickland, Lincoln N., Faraoni, Erika Y., Ruan, Wei, Yuan, Xiaoyi, Eltzschig, Holger K., Bailey-Lundberg, Jennifer M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175829/ https://www.ncbi.nlm.nih.gov/pubmed/37187740 http://dx.doi.org/10.3389/fimmu.2023.1163585

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