PGE(2) alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate

Prostaglandin E2 (PGE(2)) and 16,16-dimethyl-PGE(2) (dmPGE(2)) are important regulators of hematopoietic stem and progenitor cell (HSPC) fate and offer potential to enhance stem cell therapies [C. Cutler et al. Blood 122, 3074–3081(2013); W. Goessling et al. Cell Stem Cell 8, 445–458 (2011); W. Goes...

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Detalles Bibliográficos
Autores principales: Sporrij, Audrey, Choudhuri, Avik, Prasad, Meera, Muhire, Brejnev, Fast, Eva M., Manning, Margot E., Weiss, Jodi D., Koh, Michelle, Yang, Song, Kingston, Robert E., Tolstorukov, Michael Y., Clevers, Hans, Zon, Leonard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175842/
https://www.ncbi.nlm.nih.gov/pubmed/37126722
http://dx.doi.org/10.1073/pnas.2220613120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175842/
https://www.ncbi.nlm.nih.gov/pubmed/37126722
http://dx.doi.org/10.1073/pnas.2220613120

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