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Intact Recognition Memory and Altered Hippocampal Glucocorticoid Receptor Signaling in Fkbp5-deficient Mice Following Acute Uncontrollable Stress

The FK506 binding protein 5 (FKBP5) is a co-chaperone that regulates the activity of the glucocorticoid receptor (GR) and has been reported to mediate stress resilience. This study aimed to determine the effects of Fkbp5 deletion on acute stress-induced recognition memory impairment and hippocampal...

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Detalles Bibliográficos
Autores principales: Jeon, Yong-Jae, Choi, Bo-Ryoung, Park, Min-Sun, Jang, Yoon-Sun, Yoon, Sujung, Lyoo, In Kyoon, Han, Jung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175958/
https://www.ncbi.nlm.nih.gov/pubmed/37164649
http://dx.doi.org/10.5607/en23006