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NQO1 regulates expression and alternative splicing of apoptotic genes associated with Alzheimer's disease in PC12 cells

PURPOSE: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and cognitive dysfunction. Quinone oxidoreductase 1 (NQO1) is an antioxidant enzyme that plays an important role in controlling cellular redox state, whose expression is altered in the bra...

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Detalles Bibliográficos
Autores principales: Du, Yingshi, Liu, Gejing, Chen, Dong, Yang, Jinggang, Wang, Jing, Sun, Yue, Zhang, Qian, Liu, Yongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175992/
https://www.ncbi.nlm.nih.gov/pubmed/37002649
http://dx.doi.org/10.1002/brb3.2917