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Small extracellular vesicles derived from four dimensional-culture of mesenchymal stem cells induce alternatively activated macrophages by upregulating IGFBP2/EGFR to attenuate inflammation in the spinal cord injury of rats

Effectively reducing the inflammatory response after spinal cord injury (SCI) is a challenging clinical problem and the subject of active investigation. This study employed a porous scaffold-based three dimensional long-term culture technique to obtain human umbilical cord mesenchymal stem cell (hUC...

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Detalles Bibliográficos
Autores principales: Wang, Junhua, Wei, Qingshuai, Yang, Yue, Che, Mingtian, Ma, Yuanhuan, Peng, Lizhi, Yu, Haiyang, Shi, Huijuan, He, Guanheng, Wu, Rongjie, Zeng, Ting, Zeng, Xiang, Ma, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176095/
https://www.ncbi.nlm.nih.gov/pubmed/37187882
http://dx.doi.org/10.3389/fbioe.2023.1146981