Cargando…

Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network

The epidermal growth factor receptor (EGFR) has been studied extensively because of its critical role in cellular signaling and association with disease. Previous models have elucidated interactions between EGFR and downstream adaptor proteins or showed phenotypes affected by EGFR. However, the link...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerritsen, Jacqueline S, Faraguna, Joseph S, Bonavia, Rudy, Furnari, Frank B, White, Forest M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176108/
https://www.ncbi.nlm.nih.gov/pubmed/37169593
http://dx.doi.org/10.26508/lsa.202201466