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Methylation of lysine 36 on histone H3 is required to control transposon activities in somatic cells

Transposable elements constitute a substantial portion of most eukaryotic genomes and their activity can lead to developmental and neuronal defects. In the germline, transposon activity is antagonized by the PIWI-interacting RNA pathway tasked with repression of transposon transcription and degradin...

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Detalles Bibliográficos
Autores principales: Lindehell, Henrik, Schwartz, Yuri B, Larsson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176111/
https://www.ncbi.nlm.nih.gov/pubmed/37169594
http://dx.doi.org/10.26508/lsa.202201832