Survivin inhibition with YM155 ameliorates experimental pulmonary arterial hypertension

Background: Imbalance between cell proliferation and apoptosis underlies the development of pulmonary arterial hypertension (PAH). Current vasodilator treatment of PAH does not target the uncontrolled proliferative process in pulmonary arteries. Proteins involved in the apoptosis pathway may play a...

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Detalles Bibliográficos
Autores principales: Blanco, Isabel, Marquina, Maribel, Tura-Ceide, Olga, Ferrer, Elisabet, Ramírez, Ana M., Lopez-Meseguer, Manuel, Callejo, Maria, Perez-Vizcaino, Francisco, Peinado, Victor Ivo, Barberà, Joan Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176173/
https://www.ncbi.nlm.nih.gov/pubmed/37188265
http://dx.doi.org/10.3389/fphar.2023.1145994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176173/
https://www.ncbi.nlm.nih.gov/pubmed/37188265
http://dx.doi.org/10.3389/fphar.2023.1145994

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