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Trigeminal nerve-derived substance P regulates limbal stem cells by the PI3K-AKT pathway
Trigeminal nerve-derived substance P (SP), a widespread neuropeptide, is known to maintain the corneal epithelial homeostasis and promote the closure of wound healing. Using comprehensive in vivo and in vitro assays and RNA-sequencing analysis, we aimed to unveil the positive effects of SP on the bi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176256/ https://www.ncbi.nlm.nih.gov/pubmed/37187698 http://dx.doi.org/10.1016/j.isci.2023.106688 |