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Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions
Human trophoblast stem cells (hTSCs) have emerged as a powerful tool to model early placental development in vitro. Analogous to the epithelial cytotrophoblast in the placenta, hTSCs can differentiate into cells of the extravillous trophoblast (EVT) lineage or the multinucleate syncytiotrophoblast (...
Autores principales: | Karakis, Victoria, Jabeen, Mahe, Britt, John W., Cordiner, Abigail, Mischler, Adam, Li, Feng, San Miguel, Adriana, Rao, Balaji M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176266/ https://www.ncbi.nlm.nih.gov/pubmed/36972789 http://dx.doi.org/10.1016/j.jbc.2023.104650 |
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