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Copper boosts pro-inflammatory state of macrophages

Copper(ii) ions promote the metabolic and epigenetic remodelling of macrophages towards a pro-inflammatory state. A copper-binding metformin dimer showed promising results in mouse models of inflammation.

Detalles Bibliográficos
Autor principal: Flemming, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176277/
https://www.ncbi.nlm.nih.gov/pubmed/37173540
http://dx.doi.org/10.1038/s41577-023-00889-3