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Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease

RATIONALE: Eosinophils are associated with airway inflammation in respiratory disease. Eosinophil production and survival is controlled partly by interleukin-5: anti-interleukin-5 agents reduce asthma and response correlates with baseline eosinophil counts. However, whether raised eosinophils are ca...

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Detalles Bibliográficos
Autores principales: Guyatt, Anna, John, Catherine, Williams, Alexander T, Shrine, Nick, Reeve, Nicola F, Sayers, Ian, Hall, Ian, Wain, Louise V, Sheehan, Nuala, Dudbridge, Frank, Tobin, Martin D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176352/
https://www.ncbi.nlm.nih.gov/pubmed/35537820
http://dx.doi.org/10.1136/thoraxjnl-2021-217993