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Placental mesenchymal stem cells boost M2 alveolar over M1 bone marrow macrophages via IL-1β in Klebsiella-mediated acute respiratory distress syndrome

RATIONALE: Acute respiratory distress syndrome (ARDS) is a lethal complication of severe bacterial pneumonia due to the inability to dampen overexuberant immune responses without compromising pathogen clearance. Both of these processes involve tissue-resident and bone marrow (BM)–recruited macrophag...

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Detalles Bibliográficos
Autores principales: Wang, Li-Tzu, Yen, B Linju, Wang, Hsiu-Huan, Chao, Ying-Yin, Lee, Wei, Huang, Li-Yueh, Chiu, Sheng-Kang, Siu, L. Kristopher, Liu, Ko-Jiunn, Sytwu, Huey-Kang, Yen, Men-Luh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176360/
https://www.ncbi.nlm.nih.gov/pubmed/35450943
http://dx.doi.org/10.1136/thoraxjnl-2021-217928