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PLX8394, a RAF inhibitor, inhibits enterovirus 71 replication by blocking RAF/MEK/ERK signaling

Enterovirus 71 (EV71) poses a serious threat to human health, with scattered outbreaks worldwide. There are several vaccines against a few EV71 strains but no efficient drug for the treatment of EV71 infection. Therefore, it is urgent and of significance to develop anti-EV71 drugs. Here, we found th...

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Detalles Bibliográficos
Autores principales: Wu, Chengyuan, Zhu, Guangyan, Qiu, Fang, Ren, Fuli, Lin, Binbin, Zhang, Dingyu, Yang, Qingyu, Huang, Chaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176437/
https://www.ncbi.nlm.nih.gov/pubmed/36669700
http://dx.doi.org/10.1016/j.virs.2023.01.006