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Three-Component Approach to Densely Functionalized Trifluoromethyl Allenols by Asymmetric Organocatalysis
[Image: see text] We have developed a new three-component catalytic coupling reaction of alkynyl boronates, diazomethanes, and aliphatic/aromatic ketones in the presence of BINOL derivatives. The reaction proceeds with a remarkably high enantio- and diastereoselectivity (up to three contiguous stere...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176480/ https://www.ncbi.nlm.nih.gov/pubmed/37126044 http://dx.doi.org/10.1021/jacs.3c02852 |