Nickel Meets Aryl Thianthrenium Salts: Ni(I)-Catalyzed Halogenation of Arenes

[Image: see text] Herein, a regioselective, late-stage two-step arene halogenation method is reported. We propose how unusual Ni(I)/(III) catalysis is enabled by a combination of aryl thianthrenium and Ni redox properties that is hitherto unachieved with other (pseudo)halides. The catalyst is access...

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Detalles Bibliográficos
Autores principales: Ni, Shengyang, Yan, Jiyao, Tewari, Srija, Reijerse, Edward J., Ritter, Tobias, Cornella, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176483/
https://www.ncbi.nlm.nih.gov/pubmed/37126771
http://dx.doi.org/10.1021/jacs.3c02611
Descripción
Sumario:[Image: see text] Herein, a regioselective, late-stage two-step arene halogenation method is reported. We propose how unusual Ni(I)/(III) catalysis is enabled by a combination of aryl thianthrenium and Ni redox properties that is hitherto unachieved with other (pseudo)halides. The catalyst is accessed in situ from inexpensive NiCl(2)·6(H(2)O) and zinc without the need of supporting ligands.

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