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Glycan Stability and Flexibility: Thermodynamic and Kinetic Characterization of Nonconventional Hydrogen Bonding in Lewis Antigens

[Image: see text] We provide evidence for CH-based nonconventional hydrogen bonds (H-bonds) for 10 Lewis antigens and two of their rhamnose analogues. We also characterize the thermodynamics and kinetics of the H-bonds in these molecules and present a plausible explanation for the presence of noncon...

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Detalles Bibliográficos
Autores principales: Kwon, Jeahoo, Ruda, Alessandro, Azurmendi, Hugo F., Zarb, Jasmin, Battistel, Marcos D., Liao, Liang, Asnani, Ari, Auzanneau, France-Isabelle, Widmalm, Göran, Freedberg, Darón I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176581/
https://www.ncbi.nlm.nih.gov/pubmed/37099481
http://dx.doi.org/10.1021/jacs.2c13104