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Venetoclax combined with daunorubicin and cytarabine (2 + 6) as induction treatment in adults with newly diagnosed acute myeloid leukemia: a phase 2, multicenter, single-arm trial

BACKGROUND: Venetoclax (Ven) combined with intensive chemotherapy was proven effective in the management of acute myeloid leukemia (AML). However, the severe and prolonged myelosuppression remains a concern to worry about. To explore more appropriate combination regimens, we designed Ven combining d...

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Detalles Bibliográficos
Autores principales: Suo, Xiaohui, Zheng, Fang, Wang, Dongmei, Zhao, Liyun, Liu, Jie, Li, Ling, Zhang, Zhihua, Zhang, Congcong, Li, Yinling, Yang, Sisi, Zhao, Xuemei, Shi, Rui, Wu, Yan, Jiao, Zongjiu, Song, Jiaojie, Zhang, Ling, Lu, Xinxiao, Yuan, Linyu, Gao, Sifeng, Zhang, Jilei, Zhao, Xingli, Bai, Guanchen, Liu, Kaiqi, Mi, Yingchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176670/
https://www.ncbi.nlm.nih.gov/pubmed/37173750
http://dx.doi.org/10.1186/s40164-023-00409-y