Differential effect of histone H3.3 depletion on retroviral repression in embryonic stem cells

BACKGROUND: Integration of retroviruses into the host genome can impair the genomic and epigenomic integrity of the cell. As a defense mechanism, epigenetic modifications on the proviral DNA repress retroviral sequences in mouse embryonic stem cells (ESC). Here, we focus on the histone 3 variant H3....

Descripción completa

Detalles Bibliográficos
Autores principales: Tal, Ayellet, Aguilera, Jose David, Bren, Igor, Strauss, Carmit, Schlesinger, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176700/
https://www.ncbi.nlm.nih.gov/pubmed/37170146
http://dx.doi.org/10.1186/s13148-023-01499-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176700/
https://www.ncbi.nlm.nih.gov/pubmed/37170146
http://dx.doi.org/10.1186/s13148-023-01499-5

Ejemplares similares