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ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1

BACKGROUND: ISGylation is a post-translational protein modification that regulates many life activities, including immunomodulation, antiviral responses, and embryo implantation. The exact contribution of ISGylation to folliculogenesis remains largely undefined. RESULTS: Here, Isg15 knockout in mice...

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Detalles Bibliográficos
Autores principales: Chen, Yaru, Zhou, Jiawei, Wu, Shang, Wang, Lei, Chen, Gaogui, Chen, Dake, Peng, Xianwen, Miao, Yi-Liang, Mei, Shuqi, Li, Fenge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176748/
https://www.ncbi.nlm.nih.gov/pubmed/37170317
http://dx.doi.org/10.1186/s13578-023-01024-4