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ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1
BACKGROUND: ISGylation is a post-translational protein modification that regulates many life activities, including immunomodulation, antiviral responses, and embryo implantation. The exact contribution of ISGylation to folliculogenesis remains largely undefined. RESULTS: Here, Isg15 knockout in mice...
Autores principales: | Chen, Yaru, Zhou, Jiawei, Wu, Shang, Wang, Lei, Chen, Gaogui, Chen, Dake, Peng, Xianwen, Miao, Yi-Liang, Mei, Shuqi, Li, Fenge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176748/ https://www.ncbi.nlm.nih.gov/pubmed/37170317 http://dx.doi.org/10.1186/s13578-023-01024-4 |
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