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A positive feedback loop between ID3 and PPARγ via DNA damage repair regulates the efficacy of radiotherapy for rectal cancer

OBJECTIVE: To study the effect of inhibitor of differentiation 3 (ID3) on radiotherapy in patients with rectal cancer and to explore its primary mechanism. METHODS: Cell proliferation and clonogenic assays were used to study the relationship between ID3 and radiosensitivity. Co-immunoprecipitation a...

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Detalles Bibliográficos
Autores principales: Huang, Chuanzhong, Wang, Ling, Chen, Huijing, Fu, Wankai, Shao, Lingdong, Zhou, Dongmei, Wu, Junxin, Ye, Yunbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176823/
https://www.ncbi.nlm.nih.gov/pubmed/37170184
http://dx.doi.org/10.1186/s12885-023-10874-7