Enhanced primary ciliogenesis via mitochondrial oxidative stress activates AKT to prevent neurotoxicity in HSPA9/mortalin-depleted SH-SY5Y cells

The primary cilium, an antenna-like structure on the cell surface, acts as a mechanical and chemical sensory organelle. Primary cilia play critical roles in sensing the extracellular environment to coordinate various developmental and homeostatic signaling pathways. Here, we showed that the depletio...

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Detalles Bibliográficos
Autores principales: Bae, Ji-Eun, Jang, Soyoung, Kim, Joon Bum, Hyung, Hyejin, Park, Na Yeon, Kim, Yong Hwan, Kim, So Hyun, Kim, Seong Hyun, Ha, Jin Min, Oh, Gyeong Seok, Park, Kyuhee, Jeong, Kwiwan, Jang, Jae Seon, Jo, Doo Sin, Kim, Pansoo, Lee, Hyun-Shik, Ryoo, Zae Young, Cho, Dong-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176837/
https://www.ncbi.nlm.nih.gov/pubmed/37170364
http://dx.doi.org/10.1186/s13041-023-01029-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176837/
https://www.ncbi.nlm.nih.gov/pubmed/37170364
http://dx.doi.org/10.1186/s13041-023-01029-7

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