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Cross-phyla protein annotation by structural prediction and alignment

BACKGROUND: Protein annotation is a major goal in molecular biology, yet experimentally determined knowledge is typically limited to a few model organisms. In non-model species, the sequence-based prediction of gene orthology can be used to infer protein identity; however, this approach loses predic...

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Detalles Bibliográficos
Autores principales: Ruperti, Fabian, Papadopoulos, Nikolaos, Musser, Jacob M., Mirdita, Milot, Steinegger, Martin, Arendt, Detlev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176882/
https://www.ncbi.nlm.nih.gov/pubmed/37173746
http://dx.doi.org/10.1186/s13059-023-02942-9