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Cross-phyla protein annotation by structural prediction and alignment
BACKGROUND: Protein annotation is a major goal in molecular biology, yet experimentally determined knowledge is typically limited to a few model organisms. In non-model species, the sequence-based prediction of gene orthology can be used to infer protein identity; however, this approach loses predic...
Autores principales: | Ruperti, Fabian, Papadopoulos, Nikolaos, Musser, Jacob M., Mirdita, Milot, Steinegger, Martin, Arendt, Detlev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176882/ https://www.ncbi.nlm.nih.gov/pubmed/37173746 http://dx.doi.org/10.1186/s13059-023-02942-9 |
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