A statistical approach for identifying primary substrates of ZSWIM8-mediated microRNA degradation in small-RNA sequencing data

BACKGROUND: One strategy for identifying targets of a regulatory factor is to perturb the factor and use high-throughput RNA sequencing to examine the consequences. However, distinguishing direct targets from secondary effects and experimental noise can be challenging when confounding signal is pres...

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Detalles Bibliográficos
Autores principales: Wang, Peter Y., Bartel, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176919/
https://www.ncbi.nlm.nih.gov/pubmed/37170259
http://dx.doi.org/10.1186/s12859-023-05306-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176919/
https://www.ncbi.nlm.nih.gov/pubmed/37170259
http://dx.doi.org/10.1186/s12859-023-05306-z

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