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Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has a low survival, its incidence is rising and little therapeutic improvements are expected in the near future. It has been observed that Epithelial-to-Mesenchymal transition (EMT) contributes (including in PDAC) to a more aggressive cancer phenot...

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Detalles Bibliográficos
Autores principales: van Pelt, Jos, Meeusen, Bob, Derua, Rita, Guffens, Liesbeth, Van Cutsem, Eric, Janssens, Veerle, Verslype, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176933/
https://www.ncbi.nlm.nih.gov/pubmed/37170215
http://dx.doi.org/10.1186/s12967-023-04145-z