Decoding enhancer complexity with machine learning and high-throughput discovery

Enhancers are genomic DNA elements controlling spatiotemporal gene expression. Their flexible organization and functional redundancies make deciphering their sequence-function relationships challenging. This article provides an overview of the current understanding of enhancer organization and evolu...

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Detalles Bibliográficos
Autores principales: Smith, Gabrielle D., Ching, Wan Hern, Cornejo-Páramo, Paola, Wong, Emily S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176946/
https://www.ncbi.nlm.nih.gov/pubmed/37173718
http://dx.doi.org/10.1186/s13059-023-02955-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10176946/
https://www.ncbi.nlm.nih.gov/pubmed/37173718
http://dx.doi.org/10.1186/s13059-023-02955-4

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