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Regulation of VEGFR2 and AKT Signaling by Musashi-2 in Lung Cancer

SIMPLE SUMMARY: Lung cancer is the most common and lethal malignancy worldwide. Musashi-2 (MSI2) is an RNA-binding protein that is overexpressed in advanced NSCLC. VEGFR2 protein expression contributes to NSCLC progression and several FDA-approved drugs are used to target it in the clinic. Here, we...

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Detalles Bibliográficos
Autores principales: Bychkov, Igor, Topchu, Iuliia, Makhov, Petr, Kudinov, Alexander, Patel, Jyoti D., Boumber, Yanis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177017/
https://www.ncbi.nlm.nih.gov/pubmed/37173995
http://dx.doi.org/10.3390/cancers15092529