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Neuronal Cannabinoid CB(1) Receptors Suppress the Growth of Melanoma Brain Metastases by Inhibiting Glutamatergic Signalling

SIMPLE SUMMARY: An estimated 60% of melanoma patients develop melanoma brain metastases (MBMs). However, the molecular factors that govern the growth of MBMs are still unknown. The excitatory neurotransmitter glutamate has been shown to control the proliferation of various types of cancer cells with...

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Detalles Bibliográficos
Autores principales: Costas-Insua, Carlos, Seijo-Vila, Marta, Blázquez, Cristina, Blasco-Benito, Sandra, Rodríguez-Baena, Francisco Javier, Marsicano, Giovanni, Pérez-Gómez, Eduardo, Sánchez, Cristina, Sánchez-Laorden, Berta, Guzmán, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177062/
https://www.ncbi.nlm.nih.gov/pubmed/37173906
http://dx.doi.org/10.3390/cancers15092439