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Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells

Mast cells (MCs) are key effector cells in allergic and inflammatory diseases, and the SCF/KIT axis regulates most aspects of the cells’ biology. Using terminally differentiated skin MCs, we recently reported on proteome-wide phosphorylation changes initiated by KIT dimerization. C1orf186/RHEX was r...

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Detalles Bibliográficos
Autores principales: Franke, Kristin, Bal, Gürkan, Li, Zhuoran, Zuberbier, Torsten, Babina, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177086/
https://www.ncbi.nlm.nih.gov/pubmed/37174705
http://dx.doi.org/10.3390/cells12091306