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TRAF6 Promotes PRMT5 Activity in a Ubiquitination-Dependent Manner
SIMPLE SUMMARY: PRMT5 is overexpressed and activated in various human cancers, including breast cancer. This study aims to dissect the mechanism underlying how PRMT5 is dysregulated in cancers. Our results demonstrate that TRAF6-mediated ubiquitination plays an important role in the regulation of PR...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177089/ https://www.ncbi.nlm.nih.gov/pubmed/37173967 http://dx.doi.org/10.3390/cancers15092501 |