Cargando…

Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits

SIMPLE SUMMARY: The use of diets with optimal levels of amino acids in animal production will cause the animal’s productive traits to be better, to have less contamination, etc. This work compares two diets: Diet MMM, with an amino acid level according to the current recommendations (M = medium leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Marín-García, Pablo Jesús, Ródenas, Luís, Martínez-Paredes, Eugenio, Moya, Vicente Javier, Cambra-López, María, Blas, Enrique, Pascual, Juan José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177110/
https://www.ncbi.nlm.nih.gov/pubmed/37174507
http://dx.doi.org/10.3390/ani13091471
_version_ 1785040560670638080
author Marín-García, Pablo Jesús
Ródenas, Luís
Martínez-Paredes, Eugenio
Moya, Vicente Javier
Cambra-López, María
Blas, Enrique
Pascual, Juan José
author_facet Marín-García, Pablo Jesús
Ródenas, Luís
Martínez-Paredes, Eugenio
Moya, Vicente Javier
Cambra-López, María
Blas, Enrique
Pascual, Juan José
author_sort Marín-García, Pablo Jesús
collection PubMed
description SIMPLE SUMMARY: The use of diets with optimal levels of amino acids in animal production will cause the animal’s productive traits to be better, to have less contamination, etc. This work compares two diets: Diet MMM, with an amino acid level according to the current recommendations (M = medium levels of lysine, methionine, and threonine, respectively), and Diet MHL, with higher levels of lysine (H), medium levels of methionine, and lower levels of threonine, which improved protein utilization in a previous experiment. This work analyzes the effects of this novel combination on performance, digestibility, and retention. Finally, it is concluded that this new combination, which reduced the excretion of urea, improves the growth rate, the feed conversion ratio, and the retention of the main nutrients in fast-growing rabbits. ABSTRACT: The main aim of this work was to evaluate a novel combination of the first limiting amino acids (lysine, methionine, and threonine) in fast-growing rabbits (combination MHL, shown to minimise levels of plasmatic urea nitrogen in previous research, medium level of lysine, high level of methionine, and low level of threonine) and compare it with current recommendations (combination MMM, medium level of all amino acids). A total of 165 weaned rabbits (28 d old) from a paternal line selected for growth rate were used in the growth trial. The effect of the diet on apparent fecal digestibility, as well as the apparent and true ileal digestibility, were studied. Nutrient retention was also determined. Although no differences in digestibility between diets were observed, animals fed with Diet MHL improved the global average daily gain (+2.3 g/d; p = 0.0482) and feed conversion ratio (−0.10; p = 0.0229). Animals fed with Diet MMM reduced the protein-to-energy ratio retained (p = 0.0086). In conclusion, Diet MHL promoted an improvement in growth traits in a paternal line. Consequently, we propose its levels of 6.4, 5.4, and 5.0 g/kg DM of true ileal digestible lysine, methionine, and threonine, respectively.
format Online
Article
Text
id pubmed-10177110
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-101771102023-05-13 Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits Marín-García, Pablo Jesús Ródenas, Luís Martínez-Paredes, Eugenio Moya, Vicente Javier Cambra-López, María Blas, Enrique Pascual, Juan José Animals (Basel) Article SIMPLE SUMMARY: The use of diets with optimal levels of amino acids in animal production will cause the animal’s productive traits to be better, to have less contamination, etc. This work compares two diets: Diet MMM, with an amino acid level according to the current recommendations (M = medium levels of lysine, methionine, and threonine, respectively), and Diet MHL, with higher levels of lysine (H), medium levels of methionine, and lower levels of threonine, which improved protein utilization in a previous experiment. This work analyzes the effects of this novel combination on performance, digestibility, and retention. Finally, it is concluded that this new combination, which reduced the excretion of urea, improves the growth rate, the feed conversion ratio, and the retention of the main nutrients in fast-growing rabbits. ABSTRACT: The main aim of this work was to evaluate a novel combination of the first limiting amino acids (lysine, methionine, and threonine) in fast-growing rabbits (combination MHL, shown to minimise levels of plasmatic urea nitrogen in previous research, medium level of lysine, high level of methionine, and low level of threonine) and compare it with current recommendations (combination MMM, medium level of all amino acids). A total of 165 weaned rabbits (28 d old) from a paternal line selected for growth rate were used in the growth trial. The effect of the diet on apparent fecal digestibility, as well as the apparent and true ileal digestibility, were studied. Nutrient retention was also determined. Although no differences in digestibility between diets were observed, animals fed with Diet MHL improved the global average daily gain (+2.3 g/d; p = 0.0482) and feed conversion ratio (−0.10; p = 0.0229). Animals fed with Diet MMM reduced the protein-to-energy ratio retained (p = 0.0086). In conclusion, Diet MHL promoted an improvement in growth traits in a paternal line. Consequently, we propose its levels of 6.4, 5.4, and 5.0 g/kg DM of true ileal digestible lysine, methionine, and threonine, respectively. MDPI 2023-04-26 /pmc/articles/PMC10177110/ /pubmed/37174507 http://dx.doi.org/10.3390/ani13091471 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Marín-García, Pablo Jesús
Ródenas, Luís
Martínez-Paredes, Eugenio
Moya, Vicente Javier
Cambra-López, María
Blas, Enrique
Pascual, Juan José
Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits
title Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits
title_full Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits
title_fullStr Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits
title_full_unstemmed Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits
title_short Effect of Increasing the Methionine Level and Reducing the Threonine Level in the Diet of Fast-Growing Rabbits
title_sort effect of increasing the methionine level and reducing the threonine level in the diet of fast-growing rabbits
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177110/
https://www.ncbi.nlm.nih.gov/pubmed/37174507
http://dx.doi.org/10.3390/ani13091471
work_keys_str_mv AT maringarciapablojesus effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits
AT rodenasluis effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits
AT martinezparedeseugenio effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits
AT moyavicentejavier effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits
AT cambralopezmaria effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits
AT blasenrique effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits
AT pascualjuanjose effectofincreasingthemethioninelevelandreducingthethreoninelevelinthedietoffastgrowingrabbits