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Functional Characterisation of the Circular RNA, circHTT(2-6), in Huntington’s Disease

Trinucleotide repeat disorders comprise ~20 severe, inherited, human neuromuscular and neurodegenerative disorders, which result from an abnormal expansion of repetitive sequences in the DNA. The most common of these, Huntington’s disease (HD), results from expansion of the CAG repeat region in exon...

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Detalles Bibliográficos
Autores principales: Gantley, Laura, Stringer, Brett W., Conn, Vanessa M., Ootsuka, Youichirou, Holds, Duncan, Slee, Mark, Aliakbari, Kamelya, Kirk, Kirsty, Ormsby, Rebecca J., Webb, Stuart T., Hanson, Adrienne, Lin, He, Selth, Luke A., Conn, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177161/
https://www.ncbi.nlm.nih.gov/pubmed/37174737
http://dx.doi.org/10.3390/cells12091337