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Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation

Diabetes mellitus (DM) is an important risk factor for dementia, which is a common neurodegenerative disorder. DM is known to activate inflammation, oxidative stress, and advanced glycation end products (AGEs) generation, all capable of inducing neuronal dysfunctions, thus participating in the neuro...

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Detalles Bibliográficos
Autores principales: Yonamine, Caio Yogi, Passarelli, Marisa, Suemoto, Claudia Kimie, Pasqualucci, Carlos Augusto, Jacob-Filho, Wilson, Alves, Venâncio Avancini Ferreira, Marie, Suely Kazue Nagahashi, Correa-Giannella, Maria Lucia, Britto, Luiz Roberto, Machado, Ubiratan Fabres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177173/
https://www.ncbi.nlm.nih.gov/pubmed/37174649
http://dx.doi.org/10.3390/cells12091250