Granulomatous and Sarcoid-like Immune-Related Adverse Events following CTLA4 and PD1 Blockade Adjuvant Therapy of Melanoma: A Combined Analysis of ECOG-ACRIN E1609 and SWOG S1404 Phase III Trials and a Literature Review

SIMPLE SUMMARY: Immune checkpoint inhibitors (ICIs) can cause granulomatous and sarcoid-like lesions (GSLs) in several organs, and limited data existing that adequately inform the incidence and severity. This study examined GSL incidence in patients with high-risk melanoma treated with CTLA4 or PD1...

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Detalles Bibliográficos
Autores principales: Eljilany, Islam, Noor, Arish, Paravathaneni, Mahati, Yassine, Ibrahim, Lee, Sandra J., Othus, Megan, Moon, James, Kirkwood, John M., Sondak, Vernon K., Ribas, Antoni, Grossmann, Kenneth F., Tarhini, Ahmad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177189/
https://www.ncbi.nlm.nih.gov/pubmed/37174027
http://dx.doi.org/10.3390/cancers15092561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177189/
https://www.ncbi.nlm.nih.gov/pubmed/37174027
http://dx.doi.org/10.3390/cancers15092561

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