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Novel Therapeutic Target Critical for SARS-CoV-2 Infectivity and Induction of the Cytokine Release Syndrome

We discovered a novel therapeutic target critical for SARS-CoV-2, cellular infectivity and the induction of the cytokine release syndrome. Here, we show that the mammalian enzyme neuraminidase-1 (Neu-1) is part of a highly conserved signaling platform that regulates the dimerization and activation o...

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Detalles Bibliográficos
Autores principales: Harless, William W., Lewis, Beth, Qorri, Bessi, Abdulkhalek, Samar, Szewczuk, Myron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177205/
https://www.ncbi.nlm.nih.gov/pubmed/37174732
http://dx.doi.org/10.3390/cells12091332