Cargando…

Protein Levels of Anti-Apoptotic Mcl-1 and the Deubiquitinase USP9x Are Cooperatively Upregulated during Prostate Cancer Progression and Limit Response of Prostate Cancer Cells to Radiotherapy

SIMPLE SUMMARY: Radiotherapy constitutes an important therapeutic option for prostate cancer. However, prostate cancer cells often acquire resistance during cancer progression, limiting the cytotoxic effects of radiotherapy. Among factors regulating sensitivity to radiotherapy are members of the Bcl...

Descripción completa

Detalles Bibliográficos
Autores principales: Hogh-Binder, Sophia A., Klein, Diana, Wolfsperger, Frederik, Huber, Stephan M., Hennenlotter, Jörg, Stenzl, Arnulf, Rudner, Justine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177233/
https://www.ncbi.nlm.nih.gov/pubmed/37173959
http://dx.doi.org/10.3390/cancers15092496