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Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neuronal degenerative condition identified via a build-up of mutant aberrantly folded proteins. The native folding of polypeptides is mediated by molecular chaperones, preventing their pathogenic aggregation. The mutant protein expression in ALS is linked wit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177248/ https://www.ncbi.nlm.nih.gov/pubmed/37174703 http://dx.doi.org/10.3390/cells12091302 |