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The Mitochondrial Permeability Transition Pore—Current Knowledge of Its Structure, Function, and Regulation, and Optimized Methods for Evaluating Its Functional State

The mitochondrial permeability transition pore (MPTP) is a calcium-dependent, ion non-selective membrane pore with a wide range of functions. Although the MPTP has been studied for more than 50 years, its molecular structure remains unclear. Short-term (reversible) opening of the MPTP protects cells...

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Detalles Bibliográficos
Autores principales: Endlicher, René, Drahota, Zdeněk, Štefková, Kateřina, Červinková, Zuzana, Kučera, Otto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177258/
https://www.ncbi.nlm.nih.gov/pubmed/37174672
http://dx.doi.org/10.3390/cells12091273