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Vinblastine/Methotrexate for Debilitating and Progressive Plexiform Neurofibroma in Children and Young Adults with Neurofibromatosis Type 1: A Phase 2 Study

SIMPLE SUMMARY: Limited effective therapies exist for the treatment of neurofibromatosis type 1 (NF1)-associated plexiform neurofibroma (PN). The aim of our prospective clinical trial was to evaluate the activity and safety of vinblastine and methotrexate (conventional cytotoxic chemotherapies) give...

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Detalles Bibliográficos
Autores principales: Kotch, Chelsea, Wagner, Kristina, Broad, J. Harris, Dombi, Eva, Minturn, Jane E., Phillips, Peter, Smith, Katherine, Li, Yimei, Jacobs, Ian N., Elden, Lisa M., Fisher, Michael J., Belasco, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177272/
https://www.ncbi.nlm.nih.gov/pubmed/37174087
http://dx.doi.org/10.3390/cancers15092621