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Proof-of-Concept for Liquid Biopsy Disease Monitoring of MYC-Amplified Group 3 Medulloblastoma by Droplet Digital PCR

SIMPLE SUMMARY: MYC is a well-described oncogene across multiple cancer types. In medulloblastoma (MB), significance is subtype-dependent and associated with a particularly dismal outcome in MYC-amplified group 3 MBs. In our study, we established a highly sensitive and specific method for the detect...

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Detalles Bibliográficos
Autores principales: Stepien, Natalia, Senfter, Daniel, Furtner, Julia, Haberler, Christine, Dorfer, Christian, Czech, Thomas, Lötsch-Gojo, Daniela, Mayr, Lisa, Hedrich, Cora, Baumgartner, Alicia, Aliotti-Lippolis, Maria, Schned, Hannah, Holler, Johannes, Bruckner, Katharina, Slavc, Irene, Azizi, Amedeo A., Peyrl, Andreas, Müllauer, Leonhard, Madlener, Sibylle, Gojo, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177279/
https://www.ncbi.nlm.nih.gov/pubmed/37173990
http://dx.doi.org/10.3390/cancers15092525