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The Pesticide Chlordecone Promotes Parkinsonism-like Neurodegeneration with Tau Lesions in Midbrain Cultures and C. elegans Worms

Chlordecone (CLD) is an organochlorine pesticide (OCP) that is currently banned but still contaminates ecosystems in the French Caribbean. Because OCPs are known to increase the risk of Parkinson’s disease (PD), we tested whether chronic low-level intoxication with CLD could reproduce certain key ch...

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Detalles Bibliográficos
Autores principales: Parrales-Macias, Valeria, Michel, Patrick P., Tourville, Aurore, Raisman-Vozari, Rita, Haïk, Stéphane, Hunot, Stéphane, Bizat, Nicolas, Lannuzel, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177284/
https://www.ncbi.nlm.nih.gov/pubmed/37174736
http://dx.doi.org/10.3390/cells12091336