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Immune Checkpoint Profiling in Humanized Breast Cancer Mice Revealed Cell-Specific LAG-3/PD-1/TIM-3 Co-Expression and Elevated PD-1/TIM-3 Secretion

SIMPLE SUMMARY: Different immunotherapies have been approved for the treatment of a multiplicity of cancers. However, a large proportion of patients do not respond or develop resistance, meaning that specified treatment combinations are required to enhance individual therapy efficiencies. A combined...

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Detalles Bibliográficos
Autores principales: Bruss, Christina, Kellner, Kerstin, Albert, Veruschka, Hutchinson, James A., Seitz, Stephan, Ortmann, Olaf, Brockhoff, Gero, Wege, Anja K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177290/
https://www.ncbi.nlm.nih.gov/pubmed/37174080
http://dx.doi.org/10.3390/cancers15092615