Acidic Growth Conditions Promote Epithelial-to-Mesenchymal Transition to Select More Aggressive PDAC Cell Phenotypes In Vitro

SIMPLE SUMMARY: Acidosis represents a key chemical marker of the Pancreatic Ductal Adenocarcinoma (PDAC) microenvironment (TME). It induces the selection of aggressive cancer cell phenotypes and promotes its progression. Here, we describe the impact of an acidic TME on different PDAC hallmarks such...

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Detalles Bibliográficos
Autores principales: Audero, Madelaine Magalì, Carvalho, Tiago Miguel Amaral, Ruffinatti, Federico Alessandro, Loeck, Thorsten, Yassine, Maya, Chinigò, Giorgia, Folcher, Antoine, Farfariello, Valerio, Amadori, Samuele, Vaghi, Chiara, Schwab, Albrecht, Reshkin, Stephan J., Cardone, Rosa Angela, Prevarskaya, Natalia, Fiorio Pla, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177299/
https://www.ncbi.nlm.nih.gov/pubmed/37174038
http://dx.doi.org/10.3390/cancers15092572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177299/
https://www.ncbi.nlm.nih.gov/pubmed/37174038
http://dx.doi.org/10.3390/cancers15092572

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