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Antiproliferative Activity of Krukovine by Regulating Transmembrane Protein 139 (TMEM139) in Oxaliplatin-Resistant Pancreatic Cancer Cells

SIMPLE SUMMARY: This study investigated the antiproliferative activity of Krukovine (KV) in oxaliplatin-resistant pancreatic cancer cells and explored the mechanism of action. KV suppresses tumor progression via the downregulation of the Erk-RPS6K-TMEM139 signaling pathway in oxaliplatin-resistant p...

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Detalles Bibliográficos
Autores principales: Lee, Jee-Hyung, Lee, Sang-Hyub, Lee, Sang-Kook, Choi, Jin-Ho, Lim, Seohyun, Kim, Min-Song, Lee, Kyung-Min, Lee, Min-Woo, Ku, Ja-Lok, Kim, Dae-Hyun, Cho, In-Rae, Paik, Woo-Hyun, Ryu, Ji-Kon, Kim, Yong-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177337/
https://www.ncbi.nlm.nih.gov/pubmed/37174108
http://dx.doi.org/10.3390/cancers15092642