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Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays

The currently accepted methods for neurotoxicity (NT) testing rely on animal studies. However, high costs and low testing throughput hinder their application for large numbers of chemicals. To overcome these limitations, in vitro methods are currently being developed based on human-induced pluripote...

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Detalles Bibliográficos
Autores principales: Hartmann, Julia, Henschel, Noah, Bartmann, Kristina, Dönmez, Arif, Brockerhoff, Gabriele, Koch, Katharina, Fritsche, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177384/
https://www.ncbi.nlm.nih.gov/pubmed/37174670
http://dx.doi.org/10.3390/cells12091270